Article

Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast Cancer

2024-08-13

Abstract excerpt

<title>Abstract</title> <p>Understanding interplay of breast cancer and microenvironment is critical. Here, we identified two transcriptomic subtypes and five immune infiltration patterns from RNA-seq and multiplex immunohistochemistry from 21 ER+/HER2- invasive lobular breast cancers. The proliferative subtype associated with increased immune infiltration especially by immunosuppressive regulatory T-cells and ma...

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Literature Corpus work: 3c0f4cad-453c-5e92-90c7-6181ef81abb7
DOI: 10.21203/rs.3.rs-4579052/v1

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