Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool.

doi:10.1371/journal.pone.0118925

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Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool.

PloS one - 1 Jan 2015

Robiou-du-Pont Sébastien, Li Aihua, Christie Shanice, Sohani Zahra N, Meyre David

Abstract excerpt

Bioinformatics tools have gained popularity in biology but little is known about their validity. We aimed to assess the early contribution of 415 single nucleotide polymorphisms (SNPs) associated with eight cardio-metabolic traits at the genome-wide significance level in adults in the Family Athe...

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