Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool.

doi:10.1371/journal.pone.0118925

Back to search

Article

Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool.

PloS one - 1 Jan 2015

Robiou-du-Pont Sébastien, Li Aihua, Christie Shanice, Sohani Zahra N, Meyre David

Abstract excerpt

Bioinformatics tools have gained popularity in biology but little is known about their validity. We aimed to assess the early contribution of 415 single nucleotide polymorphisms (SNPs) associated with eight cardio-metabolic traits at the genome-wide significance level in adults in the Family Atherosclerosis Monitoring In earLY Life (FAMILY) birth cohort. We used the popular web-based tool SNAP to assess the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polymorphism, Single Nucleotide

Share to Software

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 8 closest

Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool.PMID 25742008Read

Snapping up SNPs.Semantic proximity Read

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap.Semantic proximity Read

Genetics for clinicians: from candidate genes to whole genome scans (technological advances).Semantic proximity Read

Snap: an integrated SNP annotation platform.Semantic proximity Read

The SNP Consortium website: past, present and future.Semantic proximity Read

SNP databases.Semantic proximity Read

Re-evaluation of SNP heritability in complex human traitsSemantic proximity Read

Overview of the Rapid Response data.Semantic proximity Read