Article
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness.
Molecular medicine reports - 1 Jul 2015
Wu Dapeng, Yu Hongjie, Sun Jielin, Qi Jun, Liu Qiang, Li Ruipeng, Zheng Siqun Lily, Xu Jianfeng, Kang Jian
Abstract excerpt
Telomerase reverse transcriptase (TERT), encoded by the TERT gene, is an essential component of telomerase, essential for the maintenance of telomere DNA length, chromosomal stability and cellular immortality. The aim of the present study was to evaluate the association between common genetic variations across the TERT gene region and prostate cancer (PCa) aggressiveness in a Chinese population. A total of 12...
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