Article
Genome-wide identification of allele-specific expression in response to Streptococcus suis 2 infection in two differentially susceptible pig breeds.
Journal of applied genetics - 1 Nov 2015
Wu Huayu, Gaur Uma, Mekchay Supamit, Peng Xianwen, Li Lianghua, Sun Hua, Song Zhongxu, Dong Binke, Li Mingbo, Wimmers Klaus, Ponsuksili Siriluck, Li Kui, Mei Shuqi, Liu Guisheng
Abstract excerpt
Although allele expression imbalance has been recognized in many species, and strongly linked to diseases, no whole transcriptome allele imbalance has been detected in pigs during pathogen infections. The pathogen Streptococcus suis 2 (SS2) causes serious zoonotic disease. Different pig breeds show differential susceptibility/resistance to pathogen infection, but the biological insight is little known. Here we...
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