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Article

Cardioprotective role of growth/differentiation factor 1 in post-infarction left ventricular remodelling and dysfunction.

The Journal of pathology - 1 Jul 2015

Bao Ming-Wei, Zhang Xiao-Jing, Li Liangpeng, Cai Zhongxiang, Liu Xiaoxiong, Wan Nian, Hu Gangying, Wan Fengwei, Zhang Rui, Zhu Xueyong, Xia Hao, Li Hongliang

Abstract excerpt

Growth/differentiation factor 1 (GDF1) is a secreted glycoprotein of the transforming growth factor-β (TGF-β) superfamily that mediates cell differentiation events during embryonic development. GDF1 is expressed in several tissues, including the heart. However, the functional role of GDF1 in myocardial infarction (MI)-induced cardiac remodelling and dysfunction is not known. Here, we performed gain-of-function...

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Source

Identifiers

PMID: 25726944
DOI: 10.1002/path.4523

Genes

GDF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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