Article
Suicidal behavior in the context of disrupted rhythmicity in bipolar disorder--data from an association study of suicide attempts with clock genes.
Psychiatry research - 30 Apr 2015
Pawlak Joanna, Dmitrzak-Weglarz Monika, Maciukiewicz Malgorzata, Wilkosc Monika, Leszczynska-Rodziewicz Anna, Zaremba Dorota, Kapelski Pawel, Hauser Joanna
Abstract excerpt
Suicidal behavior exhibits both circadian and annual rhythms. We were seeking an association between selected candidate clock genes and suicidal behavior in bipolar patients. The study included 441 bipolar patients and 422 controls and we genotyped 41 SNPs of the CLOCK, ARNTL, TIMELESS, PER3 gene...
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