Article
Synthesis of nickel-iron hydrogenase in Cupriavidus metallidurans is controlled by metal-dependent silencing and un-silencing of genomic islands.
Metallomics : integrated biometal science - 1 Apr 2015
Herzberg Martin, Schüttau Marcel, Reimers Matthias, Große Cornelia, Hans-Günther-Schlegel, Nies Dietrich H
Abstract excerpt
Cupriavidus metallidurans CH34 is able to grow autotrophically as a hydrogen-oxidizing bacterium and produces nickel-dependent hydrogenases, even under heterotrophic conditions. Loss of its two native plasmids resulted in inability of the resulting strain AE104 to synthesize the hydrogenases and to grow autotrophically in phosphate-poor, Tris-buffered mineral salts medium (TMM). Three of eleven previously...
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