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Article

Interplay between seven secondary metal uptake systems is required for full metal resistance of Cupriavidus metallidurans.

Metallomics : integrated biometal science - 1 Mar 2016

Herzberg M, Bauer L, Kirsten A, Nies D H

Abstract excerpt

The beta-proteobacterium Cupriavidus metallidurans is able to grow in metal-contaminated environments due to having sophisticated metal efflux systems. Here, the contribution of all seven known secondary metal uptake systems (ZupT, PitA, CorA1, CorA2, CorA3, ZntB, HoxN) to metal resistance is characterized. In a strategic deletion approach, all ten double deletion mutants, a variety of triple and quadruple...

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PMID: 26979555
DOI: 10.1039/c5mt00295h

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