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Lead(II) resistance in Cupriavidus metallidurans CH34: interplay between plasmid and chromosomally-located functions.

Antonie van Leeuwenhoek - 1 Aug 2009

Taghavi Safiyh, Lesaulnier Celine, Monchy Sebastien, Wattiez Ruddy, Mergeay Max, van der Lelie Daniel

Abstract excerpt

Proteome and transcriptome analysis, combined with mutagenesis, were used to better understand the response of Cupriavidus metallidurans CH34 against lead(II). Structural Pb(II)-resistance genes of the pMOL30-encoded pbrUTRABCD operon formed the major line of defense against Pb(II). However, several general stress response mechanisms under the control of alternative sigma factors such as sigma24/rpoK,...

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PMID: 18953667
DOI: 10.1007/s10482-008-9289-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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