Article
Biochemical features and antiviral activity of a monomeric catalytic antibody light-chain 23D4 against influenza A virus.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2015
Hifumi Emi, Arakawa Mitsue, Matsumoto Shingo, Yamamoto Tatsuhiro, Katayama Yoshiki, Uda Taizo
Abstract excerpt
Catalytic antibodies have exhibited interesting functions against some infectious viruses such as HIV, rabies virus, and influenza virus in vitro as well as in vivo. In some cases, a catalytic antibody light chain takes on several structures from the standpoint of molecular size (monomer, dimer, etc.) and/or isoelectronic point. In this study, we prepared a monomeric 23D4 light chain by mutating the C-terminal...
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