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Article

Identification of transcriptionally active HPV infection in formalin-fixed, paraffin-embedded biopsies of oropharyngeal carcinoma.

Human pathology - 1 May 2015

Morbini Patrizia, Alberizzi Paola, Tinelli Carmine, Paglino Chiara, Bertino Giulia, Comoli Patrizia, Pedrazzoli Paolo, Benazzo Marco

Abstract excerpt

Human papillomavirus (HPV) oncogenic activity is the result of viral oncogene E6 and E7 expression in infected cells. Oncogene expression analysis is, however, not part of the routine diagnostic evaluation of HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) since it requires fresh tumor tissue. We compared the diagnostic accuracy of several methods commonly employed for HPV characterization in OPSCC...

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Identifiers

PMID: 25708613
DOI: 10.1016/j.humpath.2014.12.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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