Article
Association between SNPs of Metalloproteinases and Prostaglandin F2α Receptor Genes and Latanoprost Response in Open-Angle Glaucoma.
Ophthalmology - 1 May 2015
Ussa Fernando, Fernandez Itziar, Brion Maria, Carracedo Angel, Blazquez Francisco, Garcia Maria T, Sanchez-Jara Ana, De Juan-Marcos Lourdes, Jimenez-Carmona Soledad, Juberias Jose R, Martinez-de-la-Casa Jose M, Pastor Jose C
Abstract excerpt
PURPOSE: To determine whether single nucleotide polymorphisms (SNPs) of genes coding for matrix metalloproteinases (MMPs) and the prostaglandin F2α receptor gene (PTGFR) are related to a response to latanoprost in a white Spanish population of glaucomatous patients. DESIGN: Case-control study. PARTICIPANTS: One hundred twenty-four patients with open-angle glaucoma. METHODS: Genotyping was performed in 117...
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