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Article

Influence of PTGS1, PTGFR, and MRP4 genetic variants on intraocular pressure response to latanoprost in Chinese primary open-angle glaucoma patients.

European journal of clinical pharmacology - 1 Jan 2015

Gao Li-chen, Wang Di, Liu Fang-qun, Huang Zheng-yu, Huang Hong-guang, Wang Gui-hua, Chen Xi, Shi Qun-zhi, Hong Li, Wu Li-ping, Tang Jie

Abstract excerpt

PURPOSE: The purpose of this study is to evaluate the association between variants in prostaglandin-endoperoxide synthase 1 (PTGS1), prostaglandin F (2α) receptor (PTGFR), and multidrug resistance protein 4 (MRP4) genes and intraocular pressure (IOP) response to latanoprost in Chinese patients with primary open-angle glaucoma (POAG). METHODS: The IOP response to latanoprost was evaluated by percent IOP reduction...

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Source

Identifiers

PMID: 25339146
DOI: 10.1007/s00228-014-1769-8

Genes

PTGFR
PTGS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of PTGS1, PTGFR, and MRP4 genetic variants on intraocular pressure response to latanoprost in Chinese primary open-angle glaucoma patients.PMID 25339146Read ↗

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