Article
Genes determining the severity of cerebral palsy: the role of single nucleotide polymorphisms on the amount and structure of apolipoprotein E.
Acta paediatrica (Oslo, Norway : 1992) - 1 Jul 2015
Lien Espen, Andersen Guro, Bao Yongde, Gordish-Dressman Heather, Skranes Jon S, Blackman James A, Vik Torstein
Abstract excerpt
AIM: Apolipoprotein E (apoE) influences repair and other processes in the brain, and the apoE4 variant is a risk factor for Alzheimer's disease and for prolonged recovery following traumatic brain injury. We previously reported that specific single nucleotide polymorphisms in the APOE or TOMM40 genes affecting the structure and production of apoE were associated with epilepsy, more impaired hand function and...
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