On the in vivo significance of bacterial resistance to antimicrobial peptides.

Abstract excerpt

Antimicrobial peptides (AMPs) are at the front-line of host defense during infection and play critical roles both in reducing the microbial load early during infection and in linking innate to adaptive immunity. However, successful pathogens have developed mechanisms to resist AMPs. Although considerable progress has been made in elucidating AMP-resistance mechanisms of pathogenic bacteria in vitro, less is known...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antimicrobial Cationic Peptides
• Share to Gram-Negative Bacteria
• Share to Gram-Negative Bacterial Infections