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Article

Scavenger receptor B protects shrimp from bacteria by enhancing phagocytosis and regulating expression of antimicrobial peptides.

Developmental and comparative immunology - 1 Jul 2015

Bi Wen-Jie, Li Dian-Xiang, Xu Yi-Hui, Xu Sen, Li Jing, Zhao Xiao-Fan, Wang Jin-Xing

Abstract excerpt

Scavenger receptors (SRs) are involved in innate immunity through recognizing pathogen-associated molecular patterns (PAMPs) and in pathogenesis of diseases through interactions with damage-associated molecular patterns (DAMPs). The roles of SRs in invertebrate innate immunity still need to be elucidated. Here we identify a class B scavenger receptor from kuruma shrimp, Marsupenaeus japonicus, designated MjSR-B1....

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PMID: 25697802
DOI: 10.1016/j.dci.2015.02.001

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