Article
Autophagy regulation and its dual role in blood cancers: A novel target for therapeutic development (Review)
13 Apr 2018
Abstract excerpt
Autophagy, a physiological process in which cellular components are degraded by the lysosome for cell homeostasis, plays an important role in cell metabolism, including cell proliferation, differentiation, survival and apoptosis. Recent studies indicate that autophagy serves as a survival mechanism by eliminating misfolded proteins and attenuating DNA damage. Autophagy can also suppress tumor growth, depending...
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