Folding RaCe: a robust method for predicting changes in protein folding rates upon point mutations.

Abstract excerpt

MOTIVATION: Protein engineering methods are commonly employed to decipher the folding mechanism of proteins and enzymes. However, such experiments are exceedingly time and resource intensive. It would therefore be advantageous to develop a simple computational tool to predict changes in folding rates upon mutations. Such a method should be able to rapidly provide the sequence position and chemical nature to...

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