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LncRNA Expression Discriminates Karyotype and Predicts Survival in B-Lymphoblastic Leukemia

13 Feb 2015

Abstract excerpt

UNLABELLED: Long noncoding RNAs (lncRNA) have been found to play a role in gene regulation with dysregulated expression in various cancers. The precise role that lncRNA expression plays in the pathogenesis of B-acute lymphoblastic leukemia (B-ALL) is unknown. Therefore, unbiased microarray profiling was performed on human B-ALL specimens, and it was determined that lncRNA expression correlates with cytogenetic...

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PMID: 25681502
DOI: 10.1158/1541-7786.mcr-15-0006-t

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