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Article

Disparate independent genetic events disrupt the secondary metabolism gene perA in certain symbiotic Epichloë species.

Applied and environmental microbiology - 1 Apr 2015

Berry Daniel, Takach Johanna E, Schardl Christopher L, Charlton Nikki D, Scott Barry, Young Carolyn A

Abstract excerpt

Peramine is an insect-feeding deterrent produced by Epichloë species in symbiotic association with C3 grasses. The perA gene responsible for peramine synthesis encodes a two-module nonribosomal peptide synthetase. Alleles of perA are found in most Epichloë species; however, peramine is not produced by many perA-containing Epichloë isolates. The genetic basis of these peramine-negative chemotypes is often unknown....

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Identifiers

PMID: 25681180
DOI: 10.1128/AEM.03721-14
PMCID: PMC4375322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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