Article
What the X has to do with it: differences in regulatory variability between the sexes in Drosophila simulans.
Genome biology and evolution - 1 Apr 2014
Graze Rita M, McIntyre Lauren M, Morse Alison M, Boyd Bret M, Nuzhdin Sergey V, Wayne Marta L
Abstract excerpt
The mechanistic basis of regulatory variation and the prevailing evolutionary forces shaping that variation are known to differ between sexes and between chromosomes. Regulatory variation of gene expression can be due to functional changes within a gene itself (cis) or in other genes elsewhere in the genome (trans). The evolutionary properties of cis mutations are expected to differ from mutations affecting gene...
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