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Article

The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma

12 Feb 2015

Abstract excerpt

The generation of B cells is a complex process requiring several cellular transitions, including cell commitment and differentiation. Proper transcriptional control to establish the genetic programs characteristic of each cellular stage is essential for the correct development of B lymphocytes. Deregulation of these particular transcriptional programs may result in a block in B-cell maturation, contributing to...

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Share to Acute Myeloid Leukemia Research
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PMID: 25675295
DOI: 10.1038/cddis.2014.594

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