Article
Etravirine and Rilpivirine Drug Resistance Among HIV-1 Subtype C Infected Children Failing Non-Nucleoside Reverse Transcriptase Inhibitor-Based Regimens in South India.
AIDS research and human retroviruses - 1 Jun 2017
Saravanan Shanmugam, Kausalya Bagavathi, Gomathi Selvamurthi, Sivamalar Sathasivam, Pachamuthu Balakrishnan, Selvamuthu Poongulali, Pradeep Amrose, Sunil Solomon, Mothi Sarvode N, Smith Davey M, Kantor Rami
Abstract excerpt
We have analyzed reverse transcriptase (RT) region of HIV-1 pol gene from 97 HIV-infected children who were identified as failing first-line therapy that included first-generation non-nucleoside RT inhibitors (Nevirapine and Efavirenz) for at least 6 months. We found that 54% and 65% of the children had genotypically predicted resistance to second-generation non-nucleoside RT inhibitors drugs Etravirine (ETR) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.