Article
The relevance of epigenetics to occlusive cerebral and peripheral arterial disease.
Clinical science (London, England : 1979) - 1 May 2015
Krishna Smriti Murali, Trollope Alexandra Fay, Golledge Jonathan
Abstract excerpt
Athero-thrombosis of the arteries supplying the brain and lower limb are the main causes of stroke and limb loss. New therapies are needed to improve the outcomes of athero-thrombosis. Recent evidence suggests a role for epigenetic changes in the development and progression of ischaemic injury due to atherosclerotic occlusion of peripheral arteries. DNA hypermethylation have been associated with cardiovascular...
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