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Article

Dysregulated brain immunity and neurotrophin signaling in Rett syndrome and autism spectrum disorders.

Journal of neuroimmunology - 15 Feb 2015

Theoharides Theoharis C, Athanassiou Marianna, Panagiotidou Smaro, Doyle Robert

Abstract excerpt

Rett syndrome is a neurodevelopmental disorder, which occurs in about 1:15,000 females and presents with neurologic and communication defects. It is transmitted as an X-linked dominant linked to mutations of the methyl-CpG-binding protein (MeCP2), a gene transcription suppressor, but its definitive pathogenesis is unknown thus hindering development of effective treatments. Almost half of children with Rett...

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Identifiers

PMID: 25669997
DOI: 10.1016/j.jneuroim.2014.12.003

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BDNF
CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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