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Article

The genetics of POAG in black South Africans: a candidate gene association study.

Scientific reports - 11 Feb 2015

Williams Susan E I, Carmichael Trevor R, Allingham R Rand, Hauser Michael, Ramsay Michele

Abstract excerpt

Multiple loci have been associated with either primary open angle glaucoma (POAG) or heritable ocular quantitative traits associated with this condition. This study examined the association of these loci with POAG, with central corneal thickness (CCT), vertical cup-to-disc ratio (VCDR) and with diabetes mellitus in a group of black South Africans (215 POAG cases and 214 controls). The population was homogeneous...

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Topics

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Share to Chromosomes, Human, Pair 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Diseases, Inborn

Share to Genetic Loci

Share to Glaucoma, Open-Angle

Share to Polymorphism, Single Nucleotide

Share to South Africa

Source

Open in PubMed Open full text

Identifiers

PMID: 25669751
DOI: 10.1038/srep08378
PMCID: PMC4323640

Genes

CAV1
CAV2
MYOC
SIX1
SIX6
TMCO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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