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Article

Copy number variation profile in the placental and parental genomes of recurrent pregnancy loss families.

Scientific reports - 27 Mar 2017

Kasak Laura, Rull Kristiina, Sõber Siim, Laan Maris

Abstract excerpt

We have previously shown an extensive load of somatic copy number variations (CNVs) in the human placental genome with the highest fraction detected in normal term pregnancies. Hereby, we hypothesized that insufficient promotion of CNVs may impair placental development and lead to recurrent pregnancy loss (RPL). RPL affects ~3% of couples aiming at childbirth and idiopathic RPL represents ~50% of cases. We...

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Identifiers

PMID: 28345611
DOI: 10.1038/srep45327
PMCID: PMC5366903

Genes

MTRR
NUP98

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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