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Article

Robust expression of heterologous genes by selection marker fusion system in improved Chlamydomonas strains.

Journal of bioscience and bioengineering - 1 Sept 2015

Kong Fantao, Yamasaki Tomohito, Kurniasih Sari Dewi, Hou Liyuan, Li Xiaobo, Ivanova Nina, Okada Shigeru, Ohama Takeshi

Abstract excerpt

Chlamydomonas is a very attractive candidate plant cell factory. However, its main drawback is the difficulty to find the transformants that robustly express heterologous genes randomly inserted in the nuclear genome. We previously showed that domestic squalene synthase (SQS) gene of Chlamydomonas was much more efficiently overexpressed in a mutant strain [UV-mediated mutant (UVM) 4] than in wild type. In this...

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PMID: 25660568
DOI: 10.1016/j.jbiosc.2015.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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