Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BAD-mediated apoptotic pathway is associated with human cancer development

5 Feb 2015

Abstract excerpt

The malignant transformation of normal cells is caused in part by aberrant gene expression disrupting the regulation of cell proliferation, apoptosis, senescence and DNA repair. Evidence suggests that the Bcl-2 antagonist of cell death (BAD)-mediated apoptotic pathway influences cancer chemoresistance. In the present study, we explored the role of the BAD-mediated apoptotic pathway in the development and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments
Share to Cell death mechanisms and regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25653146
DOI: 10.3892/ijmm.2015.2091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BAD-mediated apoptotic pathway is associated with human cancer developmentPMID 25653146Read ↗

Navigating the interplay between BCL-2 family proteins, apoptosis, and autophagy in colorectal cancerSemantic proximity Read ↗

Multi‑omics identification of a novel signature for serous ovarian carcinoma in the context of 3P medicine and based on twelve programmed cell death patterns: a multi-cohort machine learning studySemantic proximity Read ↗

The Role of Death-Associated Protein Kinase-1 in Cell Homeostasis-Related ProcessesSemantic proximity Read ↗

The Inhibitor of Apoptosis Proteins as Therapeutic Targets in CancerSemantic proximity Read ↗

Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancerSemantic proximity Read ↗

Predicting prognosis and drug sensitivity of ovarian cancer patients using different Programmed cell death patternsSemantic proximity Read ↗

ADORA2A promotes proliferation and inhibits apoptosis through PI3K/AKT pathway activation in colorectal carcinomaSemantic proximity Read ↗

DNA methylation as mechanism of apoptotic resistance development in endometrial cancer patients.Semantic proximity Read ↗

BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient SurvivalSemantic proximity Read ↗

Expression patterns of cell cycle and apoptosis‐related genes in a multidrug‐resistant human colon carcinoma cell lineSemantic proximity Read ↗

Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancerSemantic proximity Read ↗

FADD as a key molecular player in cancer progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.