Article
Quantitative variability of 342 plasma proteins in a human twin population.
Molecular systems biology - 4 Feb 2015
Liu Yansheng, Buil Alfonso, Collins Ben C, Gillet Ludovic C J, Blum Lorenz C, Cheng Lin-Yang, Vitek Olga, Mouritsen Jeppe, Lachance Genevieve, Spector Tim D, Dermitzakis Emmanouil T, Aebersold Ruedi
Abstract excerpt
The degree and the origins of quantitative variability of most human plasma proteins are largely unknown. Because the twin study design provides a natural opportunity to estimate the relative contribution of heritability and environment to different traits in human population, we applied here the highly accurate and reproducible SWATH mass spectrometry technique to quantify 1,904 peptides defining 342 unique...
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