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A glycoengineered antigen exploiting a conserved protein <i>O</i> -glycosylation pathway in the <i>Burkholderia</i> genus for diagnosis of glanders infections

2020-08-28

Abstract excerpt

<h4>ABSTRACT</h4> We recently described a protein O -glycosylation pathway conserved in all species of the Burkholderia genus that results in synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins. Here, we exploited this system to construct and evaluate a diagnostic tool for glanders. Burkholderia mallei , the causative agent of glanders, is a highly infectious and fatal zoonotic...

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Literature Corpus work
6f195a84-06b6-540f-99fb-0ecb9bb65b85
DOI
10.1101/2020.08.27.271338
Open publication

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A glycoengineered antigen exploiting a conserved protein <i>O</i> -glycosylation pathway in the <i>Burkholderia</i> genus for diagnosis of glanders infectionsDOI 10.1101/2020.08.27.271338
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