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Anti-desmocollin autoantibodies in nonclassical pemphigus

1 Feb 2015

Abstract excerpt

BACKGROUND: Despite the established pathogenic role of anti-desmoglein (Dsg) antibodies in classical pemphigus, the significance of autoantibodies to another desmosomal cadherin, desmocollin (Dsc) is at present unknown. No consistent immunoassay for immunoglobulin (Ig) G autoantibodies to Dscs has been developed. OBJECTIVES: The aim of this study was to develop reliable assays to detect anti-Dsc autoantibodies....

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PMID: 25640111
DOI: 10.1111/bjd.13711

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