Article
Pemphigus herpetiformis: analysis of the autoantibody profile during the disease course with changes in the clinical phenotype.
Clinical and experimental dermatology - 1 Jun 2010
Lebeau S, Müller R, Masouyé I, Hertl M, Borradori L
Abstract excerpt
BACKGROUND: Pemphigus herpetiformis (PH) is a rare dapsone-responsive variant of pemphigus, characterized by annular and vesiculopustular cutaneous lesions. Most PH serum samples contain autoantibodies against desmoglein (Dsg)1, but not Dsg3, and the presence of the latter is almost invariably associated with mucosal involvement, as predicted based on the 'Dsg compensation theory'. METHODS: We describe a patient...
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