Article
Dual activities of emodin--DNA protectivity vs mutagenicity.
Neuro endocrinology letters - 1 Jan 2014
Sevcovicova Andrea, Bodnarova Kristina, Loderer Dusan, Imreova Petronela, Galova Eliska, Miadokova Eva
Abstract excerpt
OBJECTIVES: Emodin is a bioactive anthraquinone that has diverse biological effects. It is also known as a biosynthetic precursor of hypericin. The purpose of this study was to assess mechanisms of potential genotoxic and antioxidant effects of emodin. We also investigated the potential genotoxic effect of photoactivated emodin. METHODS: Potential genotoxicity was determined by the alkaline comet assay and the...
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