Article
A DN-mda5 transgenic zebrafish model demonstrates that Mda5 plays an important role in snakehead rhabdovirus resistance.
Developmental and comparative immunology - 1 Aug 2015
Gabor K A, Charette J R, Pietraszewski M J, Wingfield D J, Shim J S, Millard P J, Kim C H
Abstract excerpt
Melanoma Differentiation-Associated protein 5 (MDA5) is a member of the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family, which is a cytosolic pattern recognition receptor that detects viral nucleic acids. Here we show an Mda5-dependent response to rhabdovirus infection in vivo u...
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