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Article

Genomic organization, promoter activity of grass carp MDA5 and the association of its polymorphisms with susceptibility/resistance to grass carp reovirus.

Molecular immunology - 1 Apr 2012

Wang Lan, Su Jianguo, Yang Chunrong, Wan Quanyuan, Peng Limin

Abstract excerpt

MDA5 (melanoma-differentiation-associated gene 5), a member of the RLR (retinoic acid-inducible gene I-like receptor) family, plays a pivotal role in innate immunity against viral infection. In the present study, the organization of grass carp (Ctenopharyngodon idella) MDA5 (CiMDA5) gene sequence was elucidated and promoter activity of its 5'-flanking region was detected. In addition, single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22361281
DOI: 10.1016/j.molimm.2012.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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