Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of KRAS promotes the mesenchymal features of basal-type breast cancer.

Experimental & molecular medicine - 30 Jan 2015

Kim Rae-Kwon, Suh Yongjoon, Yoo Ki-Chun, Cui Yan-Hong, Kim Hyeonmi, Kim Min-Jung, Gyu Kim In, Lee Su-Jae

Abstract excerpt

Basal-type breast cancers are among the most aggressive and deadly breast cancer subtypes, displaying a high metastatic ability associated with mesenchymal features. However, the molecular mechanisms underlying the maintenance of mesenchymal phenotypes of basal-type breast cancer cells remain obs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transformation, Neoplastic
Share to Epithelial-Mesenchymal Transition
Share to Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterografts

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Share to ras Proteins

Share to Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 25633745
DOI: 10.1038/emm.2014.99
PMCID: PMC4314588

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25633745-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of KRAS promotes the mesenchymal features of basal-type breast cancer.PMID 25633745Read ↗

Behind the Wheel of Epithelial Plasticity in KRAS-Driven CancersSemantic proximity Read ↗

Mesenchymal tumor cells drive adaptive resistance of Trp53-/- breast tumor cells to inactivated mutant Kras.Semantic proximity Read ↗

The proto-oncogene KRAS is targeted by miR-200c.Semantic proximity Read ↗

Ras Signaling Is a Key Determinant for Metastatic Dissemination and Poor Survival of Luminal Breast Cancer PatientsSemantic proximity Read ↗

STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancerSemantic proximity Read ↗

STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancerSemantic proximity Read ↗

Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cellsSemantic proximity Read ↗

Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers.Semantic proximity Read ↗

KRAS Oncogenic Signaling Extends beyond Cancer Cells to Orchestrate the Microenvironment.Semantic proximity Read ↗

A “NOTCH” Deeper into the Epithelial-To-Mesenchymal Transition (EMT) Program in Breast CancerSemantic proximity Read ↗

The Met receptor tyrosine kinase and basal breast cancerSemantic proximity Read ↗

The RasGAP gene, RASAL2, is a tumor and metastasis suppressor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.