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Article

Phylodynamics and Molecular Evolution of Hepatitis A Virus During the Years 1957-2021 in Japan.

Journal of medical virology - 1 Jun 2026

Shih Yi-Cheng, Lin Marco Yung-Cheng, Hsiao Bai-Cheng, Kumada Takashi, Toyoda Hidenori, Liu Hsin-Fu

Abstract excerpt

Hepatitis A virus (HAV) remains a significant public health concern despite the availability of effective vaccines, particularly in regions experiencing epidemiological transitions. Recent HAV cases in Japan have increasingly occurred among defined risk groups rather than through large food-borne outbreaks. This study analyzed the phylodynamic patterns and molecular evolution of capsid protein sequences of HAV...

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PMID: 42304976
DOI: 10.1002/jmv.71019

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