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Article

[The importance of mutational status in prognosis and therapy of GIST].

Recenti progressi in medicina - 1 Jan 2015

Comandone Alessandro, Boglione Antonella

Abstract excerpt

GIST (gastrointestinal stromal tumor) are the most common mesenchymal tumors in gastrointestinal tract and are thought to derive from the cells of Cajal or their precursors that have a constitutional mutation in KIT and PDGFRA genes. There are KIT and PDGFRA genes mutations detected before the start of therapy that are believed to be related to GIST pathogenesis and some secondary mutations causing drug...

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Source

Identifiers

PMID: 25621775
DOI: 10.1701/1740.18950

Genes

KIT
PDGFRA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[The importance of mutational status in prognosis and therapy of GIST].PMID 25621775Read ↗

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[Gastrointestinal stromal tumor (GIST): advances in 2013].Semantic proximity Read ↗

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