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Article

Abnormal cartilage development and altered N-glycosylation in Tmem165-deficient zebrafish mirrors the phenotypes associated with TMEM165-CDG.

Glycobiology - 1 Jun 2015

Bammens Riet, Mehta Nickita, Race Valérie, Foulquier François, Jaeken Jaak, Tiemeyer Michael, Steet Richard, Matthijs Gert, Flanagan-Steet Heather

Abstract excerpt

The congenital disorders of glycosylation (CDG), a group of inherited diseases characterized by aberrant glycosylation, encompass a wide range of defects, including glycosyltransferases, glycosidases, nucleotide-sugar transporters as well as proteins involved in maintaining Golgi architecture, pH and vesicular trafficking. Mutations in a previously undescribed protein, TMEM165, were recently shown to cause a new...

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Identifiers

PMID: 25609749
DOI: 10.1093/glycob/cwv009
PMCID: PMC4410832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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