Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cryptococcal Phospholipase B1 Is Required for Intracellular Proliferation and Control of Titan Cell Morphology during Macrophage Infection

21 Jan 2015

Abstract excerpt

Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of fungal-infection-related fatalities, especially in immunocompromised hosts. Several virulence factors are known to play a major role in the pathogenesis of cryptococcal infections, including the enzyme phospholipase B1 (Plb1). Compared to other well-studied Cryptococcus neoformans virulence factors such as the polysaccharide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Nail Diseases and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25605772
DOI: 10.1128/iai.03104-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cryptococcal Phospholipase B1 Is Required for Intracellular Proliferation and Control of Titan Cell Morphology during Macrophage InfectionPMID 25605772Read ↗

Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans.Semantic proximity Read ↗

The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.Semantic proximity Read ↗

Virulence factors identified by Cryptococcus neoformans mutant screen differentially modulate lung immune responses and brain dissemination.Semantic proximity Read ↗

Sac1 links phosphoinositide turnover to cryptococcal virulenceSemantic proximity Read ↗

Sac1 links phosphoinositide turnover to cryptococcal virulenceSemantic proximity Read ↗

Cryptococcal Cell Morphology Affects Host Cell Interactions and PathogenicitySemantic proximity Read ↗

Mechanisms of Cryptococcal Virulence and PersistenceSemantic proximity Read ↗

<i>PKC1</i> Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic Fungus <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans.Semantic proximity Read ↗

Potential Role of Phospholipases in Virulence and Fungal PathogenesisSemantic proximity Read ↗

SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformansSemantic proximity Read ↗

Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host PhagocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.