Article
Activity of ticarcillin/clavulanate and piperacillin/tazobactam (YTR 830; CL-298,741) against clinical isolates and against mutants derepressed for class I beta-lactamase.
Diagnostic microbiology and infectious disease - 1 Jan 2000
Knapp C C, Sierra-Madero J, Washington J A
Abstract excerpt
Piperacillin/tazobactam (YTR 830; CL-298,741) was tested against fresh and stock clinical isolates of Gram-negative bacilli, as well as against Gram-negative bacilli that had stably derepressed Class I beta-lactamases or that were hyperproductive of non-Class I beta-lactamases. Of 63 clinical isolates of the Enterobacteriaceae with ticarcillin (plus clavulanate) minimum inhibitory concentrations (MICs) of greater...
Topics
- Bacteria
- Clavulanic Acids
- Drug Combinations
- Drug Resistance, Microbial
- Drug Therapy, Combination
- Enterobacteriaceae
- Humans
- Mutation
- Penicillanic Acid
- Penicillins