Article
Comparison of the E test and microdilution for detection of beta-lactam-resistant mutants that are stably derepressed for type I beta-lactamase.
Journal of clinical microbiology - 1 Jan 1992
Knapp C C, Washington J A
Abstract excerpt
The activities of cefotaxime, ceftazidime, piperacillin, and aztreonam were compared in the E test and broth microdilution test against 30 gram-negative bacterial mutants derepressed for type I beta-lactamases. The results demonstrated complete agreement between 24-h MICs of 80 to 83% and essenti...
Topics
- Anti-Bacterial Agents
- Colony Count, Microbial
- Enzyme Repression
- Enzyme Stability
- Gram-Negative Bacteria
- Humans
- Microbial Sensitivity Tests
- Mutation
- Penicillinase
- beta-Lactams
