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Article

Molecular and clinical analysis of TRPC6 and AGTR1 genes in patients with pulmonary arterial hypertension.

Orphanet journal of rare diseases - 21 Jan 2015

Pousada Guillermo, Baloira Adolfo, Valverde Diana

Abstract excerpt

BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare and progressive vascular disorder characterized by increased pulmonary vascular resistance and right heart failure. The aim of this study was to analyze 5'UTR region in canonical transient receptor potential isoform 6 (TRPC6) and 3'UTR region in Angiotensin II type I receptor (AGTR1) genes in patients with idiopathic and associated PAH. Correlation among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Polymorphism, Single Nucleotide

Share to Receptor, Angiotensin, Type 1

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Source

Open in PubMed Open full text

Identifiers

PMID: 25603901
DOI: 10.1186/s13023-014-0216-3
PMCID: PMC4307182

Genes

AGTR1
TRPC6
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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