Article
Polymorphism in the angiotensin II type 1 receptor (AGTR1) is associated with age at diagnosis in pulmonary arterial hypertension.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Apr 2009
Chung Wendy K, Deng Liyong, Carroll J Sheila, Mallory Nicole, Diamond Beverly, Rosenzweig Erika Berman, Barst Robyn J, Morse Jane H
Abstract excerpt
BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare, lethal disease associated with single gene disorders, connective tissue disease, exposures to anorexigens, and often, idiopathic etiology. Genes can modify the risk of PAH: (1) monogenic disorders associated with PAH are incompletely pe...
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