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Article

HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions.

Immunology and cell biology - 1 Jul 2015

Bergot Anne-Sophie, Monnet Nastasia, Le Tran Son, Mittal Deepak, Al-Kouba Jane, Steptoe Raymond J, Grimbaldeston Michele A, Frazer Ian H, Wells James W

Abstract excerpt

Atopic dermatitis is a common pruritic and inflammatory skin disorder with unknown etiology. Most commonly occurring during early childhood, atopic dermatitis is associated with eczematous lesions and lichenification, in which the epidermis becomes hypertrophied resulting in thickening of the skin. In this study, we report an atopic dermatitis-like pathophysiology results in a murine model following the...

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Identifiers

PMID: 25601274
DOI: 10.1038/icb.2014.123
PMCID: PMC4496302

Genes

TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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