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Article

Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling.

Stem cell reports - 10 Feb 2015

Kao Der-I, Lacko Lauretta A, Ding Bi-Sen, Huang Chen, Phung Kathleen, Gu Guoqiang, Rafii Shahin, Stuhlmann Heidi, Chen Shuibing

Abstract excerpt

Although endothelial cells have been shown to affect mouse pancreatic development, their precise function in human development remains unclear. Using a coculture system containing human embryonic stem cell (hESC)-derived progenitors and endothelial cells, we found that endothelial cells play a st...

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Identifiers

PMID: 25601205
DOI: 10.1016/j.stemcr.2014.12.008
PMCID: PMC4325230

Genes

EGFL7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25601205-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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