Article
Long noncoding RNA profiles of adrenocortical cancer can be used to predict recurrence.
Endocrine-related cancer - 1 Feb 2015
Glover A R, Zhao J T, Ip J C, Lee J C, Robinson B G, Gill A J, Soon P S H, Sidhu S B
Abstract excerpt
Adrenocortical carcinoma (ACC) is an aggressive malignancy with high rates of recurrence following surgical resection. Long noncoding RNAs (lncRNAs) play an important role in cancer development. Pathogenesis of adrenal tumours have been characterised by mRNA, microRNA and methylation expression signatures, but it is unknown if this extends to lncRNAs. This study describes lncRNA expression signatures in ACC,...
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