Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessing the utility of confirmatory studies following identification of large-scale genomic imbalances by microarray.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Nov 2015

Sanmann Jennifer N, Pickering Diane L, Golden Denae M, Stevens Jadd M, Hempel Thomas E, Althof Pamela A, Wiggins Michele L, Starr Lois J, Davé Bhavana J, Sanger Warren G

Abstract excerpt

PURPOSE: The identification of clinically relevant genomic dosage anomalies assists in accurate diagnosis, prognosis, and medical management of affected individuals. Technological advancements within the field, such as the advent of microarray, have markedly increased the resolution of detection; however, clinical laboratories have maintained conventional techniques for confirmation of genomic imbalances...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allelic Imbalance
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Gene Duplication

Share to Genome, Human

Share to In Situ Hybridization, Fluorescence

Share to Oligonucleotide Array Sequence Analysis

Share to Sequence Deletion

Source

Identifiers

PMID: 25590977
DOI: 10.1038/gim.2014.204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessing the utility of confirmatory studies following identification of large-scale genomic imbalances by microarray.PMID 25590977Read ↗

Diagnostic utility of array‐based comparative genomic hybridization in a clinical settingSemantic proximity Read ↗

Targeted genomic microarray analysis for identification of chromosome abnormalities in 1500 consecutive clinical cases.Semantic proximity Read ↗

Clinical application of microarray-based molecular cytogenetics: an emerging new era of genomic medicine.Semantic proximity Read ↗

Microarray-based genomic DNA profiling technologies in clinical molecular diagnostics.Semantic proximity Read ↗

Clinical utility of contemporary molecular cytogenetics.Semantic proximity Read ↗

The Utilization of Chromosomal Microarray Technologies for Hematologic Neoplasms: An ACLPS Critical Review.Semantic proximity Read ↗

Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing?Semantic proximity Read ↗

Extending the scope of diagnostic chromosome analysis: detection of single gene defects using high-resolution SNP microarrays.Semantic proximity Read ↗

Identification of chromosome abnormalities in subtelomeric regions by microarray analysis: A study of 5,380 casesSemantic proximity Read ↗

Whole‐genome microarray analysis in prenatal specimens identifies clinically significant chromosome alterations without increase in results of unclear significance compared to targeted microarraySemantic proximity Read ↗

Enhanced detection of clinically relevant genomic imbalances using a targeted plus whole genome oligonucleotide microarraySemantic proximity Read ↗

Oligonucleotide microarrays in constitutional genetic diagnosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.