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Article

Mutation stability in primary and metastatic melanoma: what we know and what we don't.

Histology and histopathology - 1 Jul 2015

Varada Sowmya, Mahalingam Meera

Abstract excerpt

Despite the efficacy and success of targeted therapies, a significant number of patients with melanoma exhibit either intrinsic or acquired resistance to these drugs. Numerous mechanisms for the development of resistance have been postulated, but the precise reason for this is not known. In this...

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Identifiers

PMID: 25585249
DOI: 10.14670/HH-11-584

Genes

BRAF
GNAQ
KIT
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25585249-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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